history
The history of the ALS Therapy Development Institute is the history of the lives of the people in the community we serve. Hundreds of families
and thousands of supporters make our important work possible each and every day. The following are a few select highlights of who we are and
where we are going. For more information on ALS TDI, please email us at info@als.net or call 617-441-7200.
1999
James Allen Heywood realizes that a gap exists in the preclinical development of therapeutics for ALS and founds the ALS Therapy Development
Institute (ALS TDI) as an independent research center with a singular focus: develop effective therapeutics that slow and stop amyotrophic
lateral sclerosis (ALS, Lou Gehrig's disease). As a 501(c)(3) nonprofit organization, ALS TDI becomes the world's first nonprofit
biotechnology company.
2001 - 2006
ALS TDI screens more potential therapeutics for ALS than all other research labs in the world combined and joins together with an international
consortium of ALS researchers to discuss the best practices for preclinical research using the animal model of disease. This effort culminates
in the publication of a comprehensive guide to the use of the SOD1G93A animal model in the journal Amyotrophic Lateral Sclerosis (Scott, et. al).
2007
ALS TDI enters into a historic partnership with MDA's Augie's Quest. The partnership is centered around the foresight and understanding
that the establishment of best practices for preclinical drug development requires significant commitment and infrastructure. The collaboration
enables ALS TDI to become a center of excellence in preclinical drug discovery and validation.
Today
Today, the Institute maintains the most robust drug development pipeline of its kind in the world with dozens of potential treatments using a
variety of therapeutic strategies.
The ALS Therapy Development Institute represents a paradigm shift in the way that drug discovery and drug development is conducted for an orphan
disease such as ALS.