Published scientific papers on clinical trials in ALS for a variety of potential treatments are listed below. Select a specific study for more detailed information.

	Study	Number of Patients	Primary Reference
Treatment:BDNF
	A controlled trial of recombinant methionyl human BDNF in ALS: The BDNF Study Gr...
	A prospective, randomized, placebo-controlled evaluation of corticoneuronal resp...	11
	A controlled trial of recombinant methionyl human BDNF in ALS: The BDNF Study Gr...	1135
Treatment:Ceftriaxone
	Report of six sporadic cases of ALS patients receiving ceftriaxone.
	Ceftriaxone is ineffective in ALS.
	Ceftriaxone in amyotrophic lateral sclerosis.
	[Failure of empirical treatment with ceftriaxone in motor neuron disease]
	Improvement of patient with amyotrophic lateral sclerosis given ceftriaxone.
	Report of six sporadic cases of ALS patients receiving ceftriaxone.
	Ceftriaxone is ineffective in ALS.
	Ceftriaxone in amyotrophic lateral sclerosis.
	[Failure of empirical treatment with ceftriaxone in motor neuron disease]
	Improvement of patient with amyotrophic lateral sclerosis given ceftriaxone.
Treatment:Celebrex
	Trial of celecoxib in amyotrophic lateral sclerosis.
Treatment:CNTF
	Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis/motor neuro...	1300 (total from 2 trials)
	Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic ...	6
Treatment:Creatine
	A randomized placebo-controlled trial of creatine in amyotrophic lateral scleros...
	A clinical trial of creatine in ALS.	104
	A randomized sequential trial of creatine in amyotrophic lateral sclerosis	175
	Effects of creatine supplementation on exercise performance and muscular strengt...	28
	A clinical trial of creatine in ALS.	104
Treatment:Cyclosporin
	A double-blind study of the effectiveness of cyclosporine in amyotrophic lateral...	74
Treatment:Deprenyl
	Double blind cross over trial with deprenyl in amyotrophic lateral sclerosis	10
Treatment:Gabapentin
	Phase III randomized trial of gabapentin in patients with amyotrophic lateral sc...	204
Treatment:Guanidine hydrochloride
	The application of guanidine hydrochloride to the treatment of degenerative nerv...
Treatment:HF0299
	Beneficial effects of intrathecal IGF-1 administration in patients with amyotrop...
Treatment:High Dose Vitamin E Therapy
	High dose vitamin E therapy in amyotrophic lateral sclerosis as add-on therapy t...	160
Treatment:hSOD1
	Intrathecal administration of recombinant human superoxide dismutase 1 in amyotr...	16 (2 with SOD1 FALS)
Treatment:IgG
	Intravenous immunoglobulin therapy in amyotrophic lateral sclerosis.	7
	Intravenous immunoglobulin therapy in amyotrophic lateral sclerosis.	7
Treatment:Intravenous immunoglobulin therapy
	Intravenous immunoglobulin therapy in amyotrophic lateral sclerosis.	7
	Effect of high-dose intravenous immunoglobulin on amyotrophic lateral sclerosis ...	9
Treatment:Melatonin
	Melatonin as a candidate compound for neuroprotection in amyotrophic lateral scl...
Treatment:Minocycline
	Placebo controlled phase II studies of minocycline in amyotrophic lateral sclero...
	A pilot trial of minocycline in amyotrophic lateral sclerosis.
Treatment:N-acetyl-L-cysteine
	Randomized, double-blind, controlled trial of acetylcysteine in amyotrophic late...	110
Treatment:Pimozide
	[Assessment of the efficacy of treatment with pimozide in patients with amyotrop...	44
	[Assessment of the efficacy of treatment with pimozide in patients with amyotrop...	44
Treatment:Prednisolone
	A randomized, double-blind, placebo-controlled trial of subcutaneously injected ...	21
	Immunosuppressive treatment of patients with amyotrophic lateral sclerosis.	21
Treatment:R(+) Pramipexole
	Reduction of oxidative stress in amyotrophic lateral sclerosis following pramipe...	12
Treatment:rHCNTF
	A double-blind placebo-controlled clinical trial of subcutaneous recombinant hum...	730
Treatment:Riluzole
	Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lat...	959
	German open label trial of riluzole 50 mg b.i.d. in treatment of amyotrophic lat...	119
	A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole St...	155
Treatment:Sulindac
	Integrative role of cPLA with COX-2 and the effect of non-steriodal anti-inflamm...
Treatment:Suppressor Transfer Factor
	[Low-molecular transfer factor and its use in the treatment of amyotrophic later...	17
	[Low-molecular transfer factor and its use in the treatment of amyotrophic later...	17
Treatment:Tetrahydroaminoacridine
	Functional and pharmacokinetic studies of tetrahydroaminoacridine in patients wi...	7
	Functional and pharmacokinetic studies of tetrahydroaminoacridine in patients wi...	7
Treatment:Therapeutic Electrical Stimulation
	A clinical trial of therapeutic electrical stimulation for amyotrophic lateral s...	1
Treatment:total lymphoid irradiation
	Trial of immunosuppression in amyotrophic lateral sclerosis using total lymphoid...	61