Observational {{label}}

Study of Electrical Impedance Myography (EIM) in ALS

Please note: All trial information reflects the latest data available from the sponsor on ClinicalTrials.gov and other public databases. However, these sources may occasionally be outdated or inaccurate. For the most current information, we recommend contacting the trial sponsor or sites directly.

Overview

Intervention or Drug Name

Sponsor

Trial Status

Phase

Randomization

Trial Duration

Route of Administration

Genetic Target

Repurposed Drugs

Approved by FDA

Approved outside USA

Is a supplement

Details

Enrollment Criteria

Time since symptom onset

Vital Capacity (FVC or SVC)

Approved Medications

Registry Listing

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Purpose

This trial aims to evaluate a newly redesigned Electrical Impedance Myography (EIM) device as a tool for measuring muscle health in people with ALS.

What participation looks like

This is a multicenter, 9-month study evaluating the effectiveness of electrical impedance myography (EIM) as a diagnostic and disease-tracking tool. In addition, the following will be studied: 1. Determine EIM device's ability to discriminate between ALS and "look-alike" non-fatal, motor-predominant syndromes; 2. Track EIM progression over time and determine the best summary EIM measure that could serve as an endpoint in future clinical trials and individual patient care; and, 3. Determine whether EIM progression is predictive of a combined outcome of survival and progression as measured by ALS Functional Rating Scale, Revised (ALSFRS-R), Hand-held Dynamometry (HHD) and Vital Capacity (VC) measures.

Eligibility criteria

Ages 35-80 years, both genders, sporadic or familial definite ALS. Accepts people with other neuromuscular diseases and healthy volunteers.

Locations

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