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The Drug Discovery Engine For ALS

The Drug Discovery
Engine For ALS

Discovering drugs – until all people with ALS have effective treatments

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Discovering drugs – until all people with ALS have effective treatments

Learn More

Drug Discovery Is What Will End ALS

The treatments in the current clinical pipeline may slow ALS for some, but they will not be enough to end ALS.

We need to discover many more treatments.

The ALS Therapy Development Institute (ALS TDI) is the largest drug discovery lab in the world focused solely on finding treatments for ALS.

Help Us Advance Drug Discovery

Can We Help You Find What You Need?

Learning more about ALS, by studying data from people with ALS, is key to discovering effective treatments.

That's why ALS TDI formed the ALS Research Collaborative (ARC), a multifaceted program designed to collect comprehensive data from people with ALS and share it with researchers around the world.

Learn more about ARC

“I support ALS TDI because not only is their focus on ALS research and finding a treatment, but ALS TDI focuses on the ALS community, those actually living with the disease. ALS TDI understands the urgency that people with ALS live with in finding a treatment and is driven by that urgency.”

- Jenny Dwyer, Member of the Board of ALS TDI, wife of Pat Dwyer, diagnosed with ALS in 2005 and passed away in 2013

“ALS TDI is one of the world's most transformative medical research institutes focused on ALS. We have applied business principles with the leadership of Dr. Fernando Vieira to find a cure for ALS! I am proud to lead that effort as its Chairman.”

- Augie Nieto, former Chairman of the Board of ALS TDI, diagnosed with ALS in 2005 and passed away in 2023.

Latest ALS Research News

Wednesday, October 4, 2023

ALS Therapy Development Institute (ALS TDI) and Corsalex Partner to Advance ALS Treatments Targeting the C9 Mutation

Monday, June 12, 2023

Announcing the Expansion of the ALS Research Collaborative (ARC)

Monday, May 1, 2023

Why Should People with ALS Participate in the ARC Study?

Tuesday, April 18, 2023

ALS TDI Publishes New Paper on Potential ALS Treatment

Wednesday, October 4, 2023

ALS Therapy Development Institute (ALS TDI) and Corsalex Partner to Advance ALS Treatments Targeting the C9 Mutation

Monday, June 12, 2023

Announcing the Expansion of the ALS Research Collaborative (ARC)

Monday, May 1, 2023

Why Should People with ALS Participate in the ARC Study?

Tuesday, April 18, 2023

ALS TDI Publishes New Paper on Potential ALS Treatment

More ALS Research News

Relentless Research

At the ALS Therapy Development Institute (ALS TDI) our sole mission is to discover and develop treatments for amyotrophic lateral sclerosis (ALS) as quickly as possible. ALS TDI is the most comprehensive drug discovery lab dedicated to ALS research. As one of the world's only nonprofit biotech companies, we are led by drug development experts and people with ALS.

ALS Research

Fueled By the Community

As a nonprofit, we are only answerable to our supporters, the ALS community. Our research is funded by the ALS community, a global network of supporters whose lives have been affected by this disease, and who are unified to end ALS. We're getting closer, but we need your help.

Help Fund Treatments

Making An Impact

Our scientific team created tegoprubart, a potential treatment for ALS that is now in clinical trials. We launched the ALS Research Collaborative (ARC) – an ambitious global initiative that is designed to accelerate ALS research by gathering comprehensive data from people with ALS and sharing it with researchers around the world. Our team is working on an urgent basis to identify more potential treatments and make them available to people living with ALS.

About Our Work