You Can Help
Contact
Clinical Trials
Search
Sign Up
Donate
You Can Help
What is ALS
Newly Diagnosed?
Treatments & ALS Drugs
Frequently Asked Questions
Glossary
ALS Research
Drug Discovery Engine
ALS Research Collaborative
ARC Data Commons
Research News
Meet Our Scientists
Translational Research
Explore Our Lab
Publications
Help Fund Treatments
Donate
Scientist Wish List
Start a Fundraiser
Events
ALS Awareness
Other Ways to Give
Corporate Opportunities
Resources
ALS Forum
ALS Trial Navigator
News
ALS Town Hall
ALS TDI Community Conversations
ALS Unfiltered
Podcasts
About Us
History
Team
Our Supporters
Schedule a Tour
Financials
Press Room
Contact Us
You Can Help
Contact
Forum
Search
Donate
Sign Up
Your support fuels our research to #EndALS!
Donate Now
The Endpoints Podcast
The Endpoints Podcast features guests from the ALS community, including people living with ALS, researchers, advocates and fundraisers.
Each episode cuts to the chase with short, digestible conversations
about the latest
research at ALS TDI
and the most closely watched
ALS clinical trials
as well as
stories from people living with ALS
with their thoughts on research, healthcare and their journey with ALS.
Select episodes of the Endpoints Podcast are now available on
Spotify
and
iTunes
. Please email
endpoints@als.net
with feedback and suggestions for future episodes.
The Endpoints theme music was created by Robert Labadie.
1/6/2020
What to know about CMAP
In this episode of the Endpoints Podcast, Dr. Theo Hatzipetros, the Director of Pharmacology at the ALS Therapy Development Institute (ALS TDI) joins us to discuss CMAP and the role it now plays at the lab. CMAP, which stands for Compound Muscle Action Potentials, is a technique used by neurologists to diagnose neuromuscular diseases and monitor disease progression. In mouse models of ALS used at the ALS TDI lab, CMAP can be used to detect and track disease progression before signs would be noticeable by Neuroscore, the traditional way of monitoring disease progression that relies on the human eye to detect it. Detecting signs of ALS earlier allows researchers to determine the efficacy of potential drugs quicker and ensures that the best drug candidates are advanced to the next stage for further testing.
Sign In to Listen
Summary
In this episode of the Endpoints Podcast, Dr. Theo Hatzipetros, the Director of Pharmacology at the ALS Therapy Development Institute (ALS TDI) joins us to discuss CMAP and the role it now plays at the lab. CMAP, which stands for Compound Muscle Action Potentials, is a technique used by neurologists to diagnose neuromuscular diseases and monitor disease progression. In mouse models of ALS used at the ALS TDI lab, CMAP can be used to detect and track disease progression before signs would be noticeable by Neuroscore, the traditional way of monitoring disease progression that relies on the human eye to detect it. Detecting signs of ALS earlier allows researchers to determine the efficacy of potential drugs quicker and ensures that the best drug candidates are advanced to the next stage for further testing.
Thank you to our Sponsors
What is ALS
ALS Research
Help Fund Treatments
Resources
About Us
Contact
Forum
Shop
Search
Donate
Sign Up
What is ALS
Overview
Newly Diagnosed?
Treatments & ALS Drugs
FAQS
Glossary
Contact
Forum
Shop
Search
Donate
Sign Up
ALS Research
Overview
Drug Discovery Engine
ALS Research Collaborative
ARC Data Commons
Research News
Meet Our Scientists
Translational Research
Explore Our Lab
Publications
Contact
Forum
Shop
Search
Donate
Sign Up
Help Fund Treatments
Overview
Donate
Scientist Wish List
Start a Fundraiser
Events
ALS Awareness
Other Ways To Give
Corporate Opportunities
Contact
Forum
Shop
Search
Donate
Sign Up
Resources
Overview
ALS Forum
ALS Trial Navigator
News
ALS Town Hall
ALS TDI Community Conversations
ALS Unfiltered
Podcasts
Contact
Forum
Shop
Search
Donate
Sign Up
About Us
Overview
History
Team
Our Supporters
Schedule a Tour
Financials
Press Room
Contact Us
Contact
Forum
Shop
Search
Donate
Sign Up
Cookie Declaration
×
Searching for ALS Clinical Trials?
Get started with our newly launched
ALS Trial Navigator!
Visit ALS Trial Navigator
Searching for ALS Clinical Trials?
Get started with our newly launched
ALS Trial Navigator!
Visit ALS Trial Navigator