Ice Bucket Challenge | ALS Therapy Development Institute

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In the summer of 2014, millions of people around the world took the #ALSIceBucketChallenge to spread awareness and raise money for ALS research. The challenge raised an estimated $135+ million worldwide, with $4 million of that going to the ALS Therapy Development Institute (ALS TDI).

There is still no cure for ALS but every dollar raised gets us closer. So, now what? We do it all over again - every August until there is a cure for every single person living with ALS.

In the summer of 2014, millions of people around the world took the #ALSIceBucketChallenge to spread awareness and raise money for ALS research. The challenge raised an estimated $135+ million worldwide, with $4 million of that going to the ALS Therapy Development Institute (ALS TDI).

There is still no cure for ALS but every dollar raised gets us closer. So, now what? We do it all over again - every August until there is a cure for every single person living with ALS.

What did the $4 million accomplish?

Thanks to the $4 million raised through the Ice Bucket Challenge we were able to make significant strides in our work to find treatments for ALS. Here's what we invested in:

Precision Medicine Program

$2 million was invested in our Precision Medicine Program, allowing us to rapidly expand the program from 25 to 300 participants. The program now has 632 people enrolled.

Anti-CD40L Antibody Development

$2 million was invested into anti-CD40L antibody development. Now called tegoprubart, the treatment successfully completed a phase 2 clinical trial in May of 2022. ALS TDI is the first nonprofit biotech in ALS to develop a potential treatment and bring it from our own lab, through FDA review and into a clinical trial.

Take the Ice Bucket Challenge

Take the Ice Bucket Challenge

take the ice bucket challenge - corey

Accept the challenge and make a donation here.
Prepare your materials.
Film it! Videos must include: Your name, who challenged you, link to our website ALS.net/icebucketchallenge, the nomination of three more people to take the challenge.
Get social! Tag @ALSTDI, those who challenged you and who you challenged. Upload your video to Facebook, YouTube, Twitter and Instagram. Use hashtag #ALSIceBucketChallenge.

See the ALS Ice Bucket Challenge