Announcing the Expansion of ALS TDI’s 2026 Marathon Program

In 2026, the ALS Therapy Development Institute (ALS TDI) is offering athletes the opportunity to run in some of the world’s most prestigious marathons – all while raising funds and awareness to help end ALS.

Whether you want to run in Paris, Boston, or Big Sur, this is more than just a chance to test your endurance. It’s a way to support the groundbreaking, community-funded research happening every day at ALS TDI. As the world’s most comprehensive nonprofit biotech focused 100% on ALS research, ALS TDI relies on passionate community members to fund our urgent work of discovering and developing effective treatments for everyone with ALS.

All applications are due by November 7, 2025, and all runners will be notified by November 21, 2025.

2026 ALS TDI Marathon Program Events

• Hoka Semi de Paris (Paris Half Marathon)
  Explore the City of Light in this breathtaking half-marathon through historic Paris neighborhoods, iconic landmarks, and cheering crowds—a perfect race for first-time international runners.
  • Date: March 8, 2026
  • Fundraising Minimum: $2,500
  • Interested runners can apply here: Paris Half Marathon Application

• Schneider Electric Marathon de Paris (Paris Full Marathon)
  The Schneider Electric Marathon de Paris is now one of the biggest marathons in the world. This iconic route winds past the Eiffel Tower, Louvre, Notre-Dame, and Champs-Élysées.
  • Date: April 12, 2026
  • Fundraising Minimum: $3,500
  • Interested runners can apply here: Paris Full Marathon Application

• Boston Marathon presented by Bank of America
  Widely regarded as the pinnacle of marathon running, the Boston Marathon is one of the world’s most prestigious – and most exclusive – races. This is your chance to earn your bib and take on Heartbreak Hill in support of ALS TDI’s mission to end ALS.
  • Date: April 20, 2026
  • Fundraising Minimum: $20,000
  • Interested runners can apply here: Boston Marathon Application

• Big Sur International Marathon
   Considered one of the most scenic marathons in the world, Big Sur offers a challenging and unforgettable coastal course along the Pacific Ocean—a bucket-list race for any marathoner.
  • Date: April 26, 2026
  • Fundraising Minimum: $3,500.
  • Interested runners can apply here: Big Sur Marathon Application 

• Big Sur International Marathon 11-Miler
   Looking for a shorter challenge? Join us for the 11-mile race – which welcomes both runners and walkers – and still experience the beauty of Big Sur while supporting ALS TDI’s life-saving research.
  • Date: April 26, 2026
  • Fundraising Minimum: $2,500
  • Interested runners can apply here: Big Sur Marathon Application 

Your Miles Matter

Every mile you run brings us closer to a world without ALS. The funds raised by ALS TDI’s marathon programming go directly toward inventing and advancing treatments for everyone with ALS. Applications for the above 2026 marathons are due by November 7, 2025.

What to Do Next:

• Donate to support the 2025 ALS TDI TCS New York City Marathon Team

• Learn more about ALS TDI and our research to end ALS