The area where the motor neurons and muscles "connect" is called the neuromuscular junction (NMJ). NMJ health and function is a crucial part of the nervous system and highly scrutinized in ALS research. This area has proven itself promising with respect to targeting treatments aimed at stabilizing the connection or even re-establishing lost connections between existing motor neuron and muscle tissue in ALS patients.
We are currently screening this molecule in high-powered, optimaly designed efficacy studies at the Institute to determine what effect it may have on stabalizing the connection between the muscle and the axon.
Topics in the Pipeline