One of our most powerful new tools in recent years for in vitro experiments are something called induced pluripotent stem cells, or iPSCs. iPSCs are created with a technique that allows scientists to take living cells, often skin cells, from an adult human and revert them to the state of a stem cell, which can then be grown into any kind other kind of cell in the body – including cells affected by ALS like motor neurons.

To further explain what an iPSC is and how we use them in our research to end ALS, we’re joined today by Dr. Kyle Denton, ALS TDI’s director of Cell biology.